The Epidemiology and Treatment of Vitiligo: A Chinese Perspective
نویسندگان
چکیده
Vitiligo is an acquired skin disorder characterized by patchy depigmentation of the skin [1]. Vitiligo affects approximately 0.5% to 2% of the population worldwide, and the prevalence appears to be equal between men and women [2,3]. The pathogenesis of vitiligo is still not fully understood and mounting evidences have suggested that it might be related to autoimmunity and oxidative stress [4]. Although neither life-threatening nor symptomatic, the effect of vitiligo can be cosmetically and psychologically devastating, resulting in low selfesteem, poor body image and other negative effects [5-7]. In this review, we focus on the epidemiology and treatment of vitiligo in China.
منابع مشابه
Molecular Genetics and Epidemiology of Vitiligo
Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...
متن کاملSerum level of vitamin D3 in vitiligo patients before and after treatment with narrow band UVB. Is there an association with treatment?
Background: Vitiligo is a pigmentation disorder of the skin characterized by the loss of melanocytes through different mechanisms. Narrow band UVB (NBUVB) is a safe and effective treatment for vitiligo that acts by inducing the synthesis of cytokines involved in melanogenesis. NBUVB appears to be involved in the treatment of vitiligo by increasing the synthesis of vitamin D, which prevents the ...
متن کاملA comparison between systemic PUVA therapy alone and combined with topical Calcipotriol in the treatment of generalized Vitiligo
Background: Vitiligo is a relatively common acquired depigmentary disorder affecting approximately 1% of general population. PUVA therapy is the most effective modality and commonly used as the primary treatment of generalized Vitiligo. Objective: To evaluate the synergistic effect of topical Calcipotriol and oral methoxalene plus PUVA in treatment of generalized Vitiligo. Patients and Me...
متن کاملA comparison between systemic psoralen plus ultraviolet A therapy and topical clobetasol in the treatment of vitiligo
Background: Topical corticosteroids and oral psoralen plus ultraviolet A radiation (PUVA therapy) are two common treatment methods for vitiligo. The aim of this study was to compare the efficacy, complications and patterns of repigmentation of these two methods. Methods: This prospective randomized clinical trial was conducted from July 2007 to October 2008. Patients with disseminated vitiligo ...
متن کاملThe effect of topical 5- fluorouracil ointment along with epidermal abrasion in treatment of vitiligo
Vitiligo is a common idiopathic acquired cutaneous pigmentary disorder resulting in depigmented skin. A wide variety of therapeutic modalities have been employed for its treatment, but none of them are satisfactory, in this study we have tested the effect of 5- fluorouracil 5FU on 54 patients with documented vitiligo in Kerman city. The following treatments were performed on three selected v...
متن کامل